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Exploring Active Pharmaceutical Ingredients (APIs), the foundation of pharmaceuticals.

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Exploring Active Pharmaceutical Ingredients (APIs), the foundation of pharmaceuticals industry. The biologically active ingredients in pharmaceuticals that have a therapeutic impact are known as active pharmaceutical ingredients, or APIs. These essential components, which come in a variety of formats like pills, injectables, capsules, and more, are what make drugs function. APIs are the foundation of contemporary pharmaceuticals, fueling the drugs that save lives and relieve suffering all across the world. These substances are the bioactive parts of a medication formulation that result in the desired therapeutic outcome. Their importance in the pharmaceutical industry goes back centuries, and it has developed into a complex area that is essential to the evolution of medicine. APIs: Their Role in Modern Medicine APIs are now used extensively in medication development and formulation. They are primarily in charge of treating and managing a variety of diseases and ailments. APIs allow for
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What are APIs (Active Pharmaceutical Ingredients)?

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  People take medicines to cure, diagnose, treat, or prevent a disease. Most medication contains a couple of ingredients. The most important one is the API, which stands for Active Pharmaceutical Ingredient. This is the actual substance in the medicine that has to do the work in your body. For example, the API in Aspirin is “acetylsalicylic acid“. This API will try to fight the pain of your fever or headache. Some medicines carry the name of the API. For instance, the API of Paracetamol is “ paracetamol “. To make a pill, you’ll need more ingredients than just the API. That’s where excipients come in. These ingredients are used to give the pill, for example, volume, a sweet flavor, or a color. The term API is not only used in the pharmaceutical industry, but also in the web developers community the term API is common. For them however, it stands for “Application Programming Interface“. other examples are: ANALGESIC :  aceclofenac , diclofenac potassium , diclofenac sodium , paracetamol
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Difference in Nicotine Delivery Between Cigarettes and Vaping

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 There’s no way around it – cigarettes are a lot more efficient when it comes to delivering nicotine into your bloodstream. It’s not really surprising – concentration per puff is higher, and smokers take more frequent puffs (there’s no point in wasting a cigarette, right?). According to a study published in Nature, it takes about 35 minutes of proactive vaping to get the same amount of nicotine into the blood as after 5 minutes of smoking a cigarette (provided that the amount of nicotine in both is equivalent). This study deals with high-end vaping products and new generation mods and tanks such as Smok Alien and Limitless tank. On the other hand, if you’re using a simple vape pen (such as our Kind V2 pen, for example) it can take a bit more to get the same results. This doesn’t mean that you should dismiss it entirely – we wholeheartedly recommend V2 to vapers who are trying to cut down on their nicotine consumption, as well as to those who don’t have extreme nicotine cravings in the
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HOW MUCH NICOTINE IS IN AN ANALOG CIGARETTE COMPARED TO A VAPE TANK?

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 A study done by the Centers for Disease Control and Prevention (CDC) has shown that Marlboro brands, which are well known and most used, contain somewhere between 19.4 and 20.3 milligrams of nicotine per gram of tobacco.  Similar to the Marlboro brand are the Newports, which have almost identical numbers. Keep in mind that these numbers are on the high end. On average, the CDC study concluded that cigarettes contain 19.2 mg per gram of tobacco. Something I should note here is that one analog cigarette contains one gram of tobacco. So that’s what you get when you light up one Marlboro — approximately 20mg of nicotine. Now… how does that translate into vapes? After all, you’re putting in your own liquid there… there are several different strengths you can choose from… and the absorption works quite differently, too. According to a bit of back-of-the-napkin math, a hit from a cigarette is equivalent to a hit from a 16mg vape juice. I can’t emphasize enough that this is not an exact scien
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IS VAPING JUISE CONTAIN NICOTINE ?

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There have been several controversies regarding the content of vape juice. This was pioneered by the recent outbreak of e-cigarette and vaping associated lung injury (EVALI) and other health complications. Most theories have linked this outbreak to the high concentration of nicotine in vapes, but information gathered from research proved otherwise. In this article, we’ll outline the components of vape juice and what is used to fill an e-cigarette. The ingredients include the following: Propylene Glycol (PG) PG is described as a thin, colorless, and odorless organic compound used as a base for vape juice. It has a long history of serving important roles in foods and household products like sodas, ice cream, and coffee drinks. PG possesses levels of therapeutic properties and are often used in medical inhalers. As a humectant (ability to absorb moisture), it combines with nicotine to create the usual throat hit effect experienced during vaping. PG is also responsible for the anti-freeze
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CONCENTRATION OF NICOTINE IN COMMERCIAL E-CIGARETTES

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 Although some e-cigarettes/e-liquids do not contain nicotine, most do, and the nicotine contents of e-cigarettes are variable. Based on vaping machine studies, higher nicotine concentration of e-liquids results in higher nicotine yield of any given e-cigarette . As with combustible tobacco cigarettes, machine-derived nicotine yield of e-cigarettes is not necessarily predictive of users' systemic exposures to nicotine. Other factors such as power of the e-cigarette and user behavior and use patterns are also critical. Nevertheless, e-liquid nicotine concentration may be a determinant of systemic nicotine exposure. Here, the committee reviews current evidence related to the range of nicotine concentrations in commercially available e-cigarettes, whether cartridges of first-generation and closed-tank e-cigarettes or refill liquids used in other open-system e-cigarettes. The committee also discusses labeling accuracy of nicotine content. There is no consensus in the way nicotine stren
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  In the New World, tobacco was both thought of as a panacea for all that could ail you and also as a spiritual conduit. Using it cured you, kept you safe, and could give you visions. And it also helped with what was more common in those days: a less reliable food supply. In other words, more people were more hungry more of the time. Tobacco, and the  nicotine  it contained, was an effective appetite suppressant and a food substitute. When you smoked, it both distracted you from thinking about food as well as suppressing the cravings. Nicotine: The Appetite Suppressant We still use tobacco as an appetite suppressant, but more to combat the desire to eat than to survive the times when food is not available. However, the poor (and supermodels) still smoke to alleviate hunger. Historically it appears that many psychoactive substances were adopted precisely because they helped alleviate hunger. Hallucinations were much more common in those days – both because of the use of tobacco (which h
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