USE OF HYDROLYSED COLLAGEN AS A NUTRACEUTICAL IN SKIN AGEING
SKIN AGEING
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| skin ageing(https://atompharma.co.in/product/fish-collagen/) |
Our skin is at the mercy of many forces as we age: sun, harsh weather, and bad habits. But we can take steps to help our skin stay supple and fresh-looking.
How your skin ages will depend on a variety of factors: your lifestyle, diet, heredity, and other personal habits.
Skin is subject to deterioration caused by dermatological
disorders, environmental conditions (wind, air conditioning,
heating) and the intrinsic ageing process, which may be
accelerated by exposure to sun (photo-ageing) or by
other lifestyle issues (extrinsic ageing: smoking, alcohol,
stress, lack of sleep and chronic sun exposure). All
these factors may cause the formation of wrinkles, the
appearance of brown spots and the thickening of the skin.
Autoimmune diseases, ageing and stress can change the
quantity and integrity of collagen in the skin as they impair
collagen quality and consequently affect the overall skin
function.
Dehydration increases the risk of skin injury. Sometimes minor nutritional deficiencies can cause rashes, skin lesions, and other skin changes, even if you have no other symptoms.
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| Collagen decreases after intrinsic and extrinsic ageing(https://atompharma.co.in/product/fish-collagen/) |
Collagen is the most abundant protein in the human body,
Where:
30% of total protein. Major
protein of connective tissues: bones, tendons, ligaments, basement membranes,
dentin, cementum, (not enamel).
Cellular location:
extracellular matrix.
Structure:
triple helix (tropocollagen). Subsequent to
secretion, tropocollagen is assembled and crosslinked to make insoluble collagen fibers.
Endogenous collagen is natural collagen, synthesized by the body. Exogenous collagen is synthetic. It comes from an outside source, such as supplements.
Endogenous collagen has a number of important functions. Breakdown and depletion is linked to a number of health problems.
Exogenous collagen is used for medical and cosmetic purposes, including the repair of body tissues.
The five most common types of collagen.
Hydrolyzed collagen consists of small peptides with low
molecular weight (0.3 - 8 kDa), produced from native
collagen which is found in bones, skin and connective tissue of animals (i.e. cattle, pigs and fish). Due to its low
molecular weight, hydrolyzed collagen is easily digestible,
absorbed and distributed in the human body.
Several experiments have shown that collagen peptides can
be efficiently absorbed and distributed to the dermis, the
deepest layer of the skin, where they can stimulate the
proliferation and motility of fibroblasts; induce an increase
in the density and diameter of collagen fibers; increase
hyaluronic acid production and activate protection against
UVA radiation.
To date several controlled clinical trials have been
performed proving the efficacy and benefits of collagen
peptides on skin properties, such as hydration, elasticity and
reduction of wrinkles and recently a number of therapeutic
formulations of hydrolysed collagen have been developed for
the treatment of skin ageing. These fall into the category of
nutraceuticals – products offering real benefits to all those
with ageing skin
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